14 best wrinkle fillers that really work including ‘Botox in a bottle’

As we get older, our skin bears the signs of ageing that many of us wish to smooth out. Fine lines and wrinkles are two of the most common skin bugbears that shoppers look to beauty brands to help iron out, using the best wrinkle fillers, serums and moisturisers. But with so many options on the market, looking for the right one can be overwhelming and it begs the question: do they really work?

In recent years, the industry has seen a tidal wave of products that claim to work miracles on these aforementioned ‘problem’ areas, with results claiming to be visible either instantly or over a few weeks of use.

We put a number of these top-rated, results-backed age-defying products to the test to see if they did what they say on the packaging. Alongside this, in our roundup, we’ve included some top rated products shoppers love for their impressive results.

From a smart ‘Botox in a bottle’ treatment to a bargain £3.79 face mask, here is our shortlist of the best products for deep wrinkles that we can say really work – and even better, loads of them are currently on sale.

Best wrinkle fillers to buy in 2025

• Dr Dennis Gross DermInfusions Fill + Repair Eye Cream: £64 from Cult Beauty
• Medik8 Liquid Peptides Advanced MP: £79 from Medik8.
• SkinCeuticals P-Tiox Neuro-Peptide Serum: £130 from LookFantastic
• RoC Derm Correxion Fill + Treat Serum: £39.99 from Sephora
• Hada Labo Tokyo Wrinkle Corrector Eye and Mouth Cream: Was £18.99, now £14.22 from Superdrug
• No7 Laboratories Line Correcting Booster Serum: £34.95 from Boots
• Elemis Pro-Collagen Morning Matrix: £128 from LookFantastic
• L’Oréal Paris 1.5% Hyaluronic Acid Revitalift Filler Serum: Was £24.99, now £19.99 from LookFantastic
• Nivea Q10 Targeted Wrinkle Filler Serum: Was £14.99 now £7.50 from Amazon
• Murad Targeted Wrinkle Corrector: £76 from Murad
• Nivea Expert Lift Cellular Sculpting Sheet Mask: Was £4.99, now £3.79 from Amazon
• Vichy Liftactiv Supreme HA Epidermic Filler: Was £43, now £32.25 from Boots
• Dior Capture Totale Retishot: £92 from Dior
• Luna Microcare Eternal Anti-Wrinkle Under Eye Patches: From £20 from Luna Microcare

Dr Dennis Gross DermInfusions Fill + Repair Eye Cream

For those looking to supercharge their eye care routine, the Dr Dennis Gross DermInfusions Fill + Repair Eye Cream is flying off the shelves at Cult Beauty for £64.

This cutting-edge formula targets six key areas around the eyes to visibly reduce signs of ageing such as crow’s feet and under-eye bags , reports OK!.

It harnesses the power of copper peptides and ectoin to smooth fine lines, protect the moisture barrier, and tighten wrinkles, as the brand promises.

A satisfied Space NK customer raved about its miraculous results and said: “I’ve only been using the Fill Repair Eye Cream for a couple of weeks, but I can already see a difference. My under-eyes look more awake and less sunken, and the fine lines are definitely softer. It has a lightweight, silky texture that absorbs quickly and layers well with other products. I love the cooling feel when I apply it – it’s super refreshing in the morning.”

They also sing high praises of its transformative effects, stating: “The hyaluronic acid really plumps up the skin, and I’ve noticed less puffiness and darkness overall. It honestly feels like a mini filler effect without the needles!”.

Medik8’s Liquid Peptides Advanced MP serum

Priced at £79, this face serum is making waves in the beauty industry with its bold claims of diminishing deep-set wrinkles within eight weeks and delivering rapid results in as little as 10 minutes. Fans of the serum, including our own beauty editor, are quick to confirm this efficiency. While one happy beauty fan said it “really works”, with others coining it “magic in a bottle”, OK! beauty editor Laura shared: “From the get-go, the serum impressed me with its elegant formulation.

“It absorbed swiftly without leaving a greasy residue, played nicely with my other skincare essentials, and stayed put under my make-up without any pilling or sliding.

“My skin felt instantly smoother after using this, and when I checked back in 10 minutes later, I did see a change; not a massive one, and lines weren’t instantly gone, but overall my skin looked a bit fresher, healthier and stronger. It won’t take the place of Botox for me (no topical skincare product can freeze muscles), but it might just keep me feeling a bit better about my skin until I get my top-up.”

SkinCeuticals P-Tiox Neuro-Peptide Serum

On the pricier side, this SkinCeuticals serum is £130 from LookFantastic but is loved by beauty editors, skincare experts and dermatologists for cult classic products like C E Ferulic.

The brand has introduced this smart serum that features a multi-peptide complex along with PHA, niacinamide and laminaria extract, aiming to target nine different types of wrinkles, from crow’s feet to forehead lines, according to SkinCeuticals.

Laura stated: “P-Tiox is such a dreamy formula: it’s lightweight and runny yet rich, it absorbs instantly yet feels super hydrating (so hydrating that I’ve been skipping moisturiser and going straight to SPF in the mornings), and it layers perfectly with all my other skincare and make-up.”

Another reviewer echoed the sentiment and said: “I’ve only been using this for a week so far but the immediate and short-term results are so impressive that I know I’m already going to be gutted when it runs out. It makes my skin look instantly fresher, plumper and brighter – we’re talking ‘glass skin’ vibes here. It’s a real ‘one-and-done’ anti-ageing serum – you can read my fill review here.”

RoC Derm Correxion Fill + Treat Serum

This anti-ageing serum by RoC, £39.99, a popular brand among celebrities like Jennifer Aniston and Sarah Jessica Parker, combines three types of hyaluronic acid for instant skin plumping and wrinkle smoothing, along with retinol to enhance cell renewal. According to RoC’s clinical trials, a remarkable 97% of participants observed a noticeable reduction in fine lines and wrinkles within minutes.

One Amazon customer shared: “Love love love love love. In the second week that I’ve been using this. I saw a huge difference in the fine lines on my face. I was skeptical at first but I can’t believe how great this stuff is.”

Hada Labo Tokyo Wrinkle Corrector Eye and Mouth Cream

This cream, featuring retinol, collagen, and four types of hyaluronic acid, has impressed shoppers with its rapid results – some reporting noticeable improvements in wrinkles, particularly around the eyes and mouth, in just four days. Superdrug shoppers are raving over these beauty results, with one customer exclaiming: “I had brought this on my friend’s recommendation, I don’t do skincare etc. I had noticed that I was getting smile wrinkles at the end for my eyes; after applying this I noticed the wrinkles had disappeared within four days of using it day and night! Will continue to use it. Highly recommended. Will look into buying what other skin products are available in this brand. 5 stars!”.

Plus, it’s on sale from £18.99 to £14.22 from Superdrug.

No7 Laboratories Line Correcting Booster Serum

One of our must-have products is No7 Laboratories Line Correcting Booster Serum, retailing at a reasonable £34.95 from Boots. Specially targeting lines and wrinkles with Matrixyl 3000+, it’s clinching rave reviews for its proven efficacy against even deep-set furrows.

As OK! beauty expert Zoe attests: “I’m in my thirties so my wrinkles aren’t exactly stubborn, but I do have one on my forehead that really bothers me. I’ve been using this serum for the past two weeks to try to smooth it out, and I’m pleased to report promising results. While the line is still there, there’s been a definite softening of it to a point where it doesn’t bother me quite so much.”

Elemis Pro-Collagen Morning Matrix

For those looking for premium care, Elemis Pro-Collagen Morning Matrix at £128 from LookFantastic offers a high-end promise to boost skin firmness and smoothness as you start your day.

One product tester, Tracy, shared their results: “Wow! I wasn’t sure what to expect and this stuff is amazing! It had the instant effect of a primer and my skin looks great. I usually look half asleep in the day but this has changed all that. I’ve been told my skin looks radiant, brighter and smoother. Seeing a difference with my lines and wrinkles after just a month has been amazing so I will definitely buy this.”

L’Oréal Paris 1.5% Hyaluronic Acid Revitalift Filler Serum

Once priced at £24.99, this celebrity-loved serum is now available for just £19.99 from LookFantastic. This serum is not only a hit among celebrities like Molly-Mae Hague but also boasts L’Oréal’s highest concentration of hyaluronic acid, ensuring deep hydration for the skin.

The Revitalift eye cream too has become a shopper’s favourite.

Laura comments: “I feel like anyone would love this serum; works well with other skincare and instantly makes the face look a little fresher and plumper. It won’t work miracles on deep wrinkles but it’s a great boost for the skin.”

Nivea Q10 Targeted Wrinkle Filler Serum

Previously £14.99, this serum is now a bargain at £8.49 from Amazon and has quickly become a must-have, selling out upon release.

Now back in stock, it features Nivea’s renowned Q10 complex and ‘Bioxifill peptides’ to rapidly smooth wrinkles, as confirmed by nine out of 10 testers. Not only does it offer an immediate smoothing effect, but Nivea also promises lasting benefits, claiming a noticeable reduction in wrinkles in key areas such as the forehead, eyes, and naso-labial folds within two weeks.

Laura raved about the product’s immediate effects, saying: “This has an instantly smoothing and blurring effect on fine lines, like Facetune in a tube. It won’t work miracles on very deep wrinkles, but for a quick fix – perhaps before a night out of an important event – it’s great. It’s worth noting that this serum isn’t particularly hydrating so use in addition to your usual serum and/or moisturiser.”

The Murad Targeted Wrinkle Corrector

Priced at £76 from Murad, this cream boasts peptides that act as instant, temporary ‘filler’ for deep lines, alongside ingredients designed to fend off future lines. The product has even caused a stir on TikTok, with users hailing it as “Botox in a bottle”.

Tester Colleen was excited to share her results and said: “This product has filled my fine lines on my forehead and my crows feet. Even the very first application my skin looked so much more radiant, healthier and a lot less wrinklier. It’s like some kind of miracle cream! It’s a must have for me now – I look younger and it gives me a plumper appearance without having cosmetic procedures.”

Nivea Expert Lift Cellular Sculpting Sheet Mask

At just £3.98 from £4.99 on Amazon, this 10-minute bakuchiol serum mask experience is aimed at firming, hydrating, and plumping the skin which diminishes wrinkle visibility.

“My skin felt really soft, definitely plumper, so much smoother and really hydrated,” said Tester Gail. “It’s everything my skin needs and I’ve been admiring my face in the mirror all day. I will definitely be buying more and I’m telling friends about it. I actually feel like I’ve had some sort of expensive facial procedure.

“Overall my skin looks plumper so there are fewer lines. Finally, an inexpensive product that stands up to the claims it makes. I absolutely love it.”

Vichy Liftactiv Supreme HA Epidermic Filler

Originally £43, this filler serum is now only £32.25 from Boots. This potent formula is packed with hyaluronic acid and vitamins to drench your skin in moisture and visibly reduce lines for a rejuvenated look.

Lisa, another tester, was equally impressed: “This left my skin looking lifted and feeling great. The bottle is great for easy application. My skin looks less wrinkly, more youthful and fresh. I absolutely love it.”

Dior Capture Totale Retishot

On the pricier side, this luxurious treatment is available for £92 at Boots. Dior’s latest innovation offers a retinol treatment that promises not just to diminish fine lines but also improve skin texture, tone, and even tackle blemishes. Its silky feel and delightful fragrance add to the allure.

One satisfied Boots customer shared their immediate results: “I was expecting to see results after a few weeks of consistent use, not after just one night! I applied Dior’s new Capture Totale Retishot before bed and woke up with the most softest skin! I can’t even remember the last time my face was this smooth! There was a little redness, but that was to be expected with pure retinol. I’m really excited to continue using this product!”.

Luna Microcare Eternal Anti-Wrinkle Under Eye Patches

These patches are the new must-have for those seeking a youthful gaze, starting at just £20 from Luna Microcare. These innovative patches work their magic overnight, featuring dissolvable micro-channels that infuse anti-ageing compounds directly into the skin.

The brand’s clinical study boasts “dramatic improvements” in wrinkle depth.

Tester Rachel was over the moon with her results and stated: “Amazing, loved it! A general appearance of tiredness around my eyes causes my makeup not to apply evenly, and makes me look and feel older. After 2-3 weeks of using these, lines around my eyes appeared less pronounced. The whole experience left me feeling more positive as now I don’t look so old and tired. I would definitely would buy this product as I saw a real improvement – the skin under my eyes look fresher and plumper.”